Healing SIBO References
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- Information on the SIBO Recovery Roadmap
- All the references in Healing SIBO!
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The SIBO Recovery Roadmap is based on the same healing algorithm Roadmap Guide you’ll find on page 111 of Healing SIBO.
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As Promised, Here Are the References from Healing SIBO
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- Recent data suggest: Mark Pimentel, MD, FRCP(C), FACG, Richard J. Saad, MD, FACG, Millie D. Long, MD, MPH, FACG (GRADE Methodologist) and Satish S. C. Rao, MD, PhD, FRCP, FACG (2020). “ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth”. American Journal of Gastroenterology 2020;00:1–14. https://doi.org/10.14309/ajg.0000000000000501; published online January 8, 2020
- 48 million people: https://www.cdc.gov/foodsafety/foodborne-germs.html
- 800 million worldwide: https://www.who.int/news-room/detail/03-12-2015-who-s-first-ever-global-estimates-of-foodborne-diseases-find-children-under-5-account-for-almost-one-third-of-deaths
- Especially IBS with diarrhea: Laine Bergesom Becco (2019). “The Food Poisoning–IBS Connection”. Experience Life August 13, 2019. https://experiencelife.com/article/the-food-poisoning-ibs-connection/
- Worsening of IBS symptoms: “Gallbladder Removal and IBS—Is There a Link?”. April 4, 2017. https://irritablebowelsyndrome.net/clinical/gallbladder-removal-ibs/
- Bottom line: You get SIBO/IBS: Laine Bergson Becco (August 13, 2019). “The Food Poisoning-IBS Connection”. Experience Life. https://experiencelife.com/article/the-food-poisoning-ibs-connection/
- protection to your muscles and bones: Larry Wurn interview with the author
- neural therapy: Tolle Causam, “Pain, Scars and Neural Therapy”. Naturopathic Doctor News and Review July 1, 2013. https://ndnr.com/pain-medicine/pain-scars-and-neural-therapy/
- If you have diverticulitis: Tursi A, Brandimarte G, Giorgetti GM, Elisei W (2005). “Assessment of small intestinal bacterial overgrowth in uncomplicated acute diverticulitis of the colon”. World Journal of Gastroenterology. 2005 May 14;11(18):2773-6. DOI: 10.3748/wjg.v11.i18.2773 https://www.ncbi.nlm.nih.gov/pubmed/15884120
- when the valve doesn’t close properly things wind up where they don’t belong: Roland BC1, Ciarleglio MM, Clarke JO, Semler JR, Tomakin E, Mullin GE, Pasricha PJ. (June 2014). “Low ileocecal valve pressure is significantly associated with small intestinal bacterial overgrowth (SIBO)”. Digestive Diseases and Sciences 59(6):1269-77. doi: 10.1007/s10620-014-3166-7. https://www.ncbi.nlm.nih.gov/pubmed/24795035
- attacking the vinculum, which then causes your migrating motor complex to stop functioning as it should: Angela Pifer, Functional Medicine Nutritionist (Dec. 1, 2015). “Ileocecal Valve Dysfunction Contributes to SIBO”. SIBO Guru. https://siboguru.com/ileocecal-valve-dysfunction-contributes-to-sibo/
- proton-pump inhibitors are at increased risk for developing SIBO: Edward J. Krajicek, MD, Stephanie L. Hansel, MD, MS (December 2016). “Small Intestinal Bacterial Overgrowth: A Primary Care Review”. Mayo Clinic Proceedings 91(12); 1828–1833. DOI: https://doi.org/10.1016/j.mayocp.2016.07.025
- hard stool, straining during bowel movement and incomplete evacuation: Wojciech Leppert (2012). “The impact of opioid analgesics on the gastrointestinal tract function and the current management possibilities”. Contemporary Oncology 16(2): 125–131. doi: 10.5114/wo.2012.28792 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687404/
- people who receive pelvic radiation develop gastrointestinal problems associated with SIBO: Ann Cecile Muls (27 Jan 2014). “Gastrointestinal consequences of cancer treatment and the wider context: A bad gut feeling”. Acta Oncologica Volume 53, 2014 Issue 3 https://www.tandfonline.com/doi/full/10.3109/0284186X.2013.873140
- damage done to the small intestine itself, bacterial overgrowth, or lactose intolerance—all of which are associated with SIBO: Rhodri Stacey and John T. Green (2014). “Radiation-induced small bowel disease: latest developments and clinical guidance”. Therapeutic Advances in Chronic Disease 2014 Jan; 5(1): 15–29. doi: 10.1177/2040622313510730 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871275/
- More severe diarrhea: Dr. Mark Pimentel interview with the author
- symptoms were indistinguishable: Dr. Allison Siebecker interview with the author
- The primary producers of methane: Ujjala Ghoshal, Ratnakar Shukla, Deepakshi Srivastava, and Uday C Ghoshal (2016). “Irritable Bowel Syndrome, Particularly the Constipation-Predominant Form, Involves an Increase in Methanobrevibacter smithii, Which Is Associated with Higher Methane Production”. Gut and Liver 10(6): 932–938. doi: 10.5009/gnl15588. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087933/
- Just as I am writing this: Mark Pimentel, MD, FRCP(C), FACG, Richard J. Saad, MD, FACG, Millie D. Long, MD, MPH, FACG (GRADE Methodologist) and Satish S. C. Rao, MD, PhD, FRCP, FACG (2020). Op cit https://doi.org/10.14309/ajg.0000000000000501; published online January 8, 2020
- The development of obesity and insulin resistance: Dr. Mark Pimentel interview with the author.
- Their reflux also improves: Dr. Steven Sandberg-Lewis interview with the author
- It could also cause malabsorption of nutrients: Oren Zaidel and Henry C. Lin (2003).
- “Uninvited Guests: The Impact of Small Intestinal Bacterial Overgrowth on Nutritional Status”. Practical Gastroenterology July 2003. https://med.virginia.edu/ginutrition/wp-content/uploads/sites/199/2015/11/zaidelarticle-July-03.pdf
- you may be suffering from hypochlorhydria or low stomach acid: Elizabeth Millard (2018). “How Low Stomach Acid Affects Diet and Fitness”. Myfitnesspal October 12, 2018. https://blog.myfitnesspal.com/how-low-stomach-acid-affects-diet-and-fitness/
- To make matters worse: SIBO and Anemia, SIBO Doctors, November 3, 2016. http://www.sibodoctors.ca/blog/2016/10/12/sibo-and-associated-health-conditions
- Indicator of low B12 levels: Dr. Steven Sandberg-Lewis interview with the author
- Indicates hypochlorhydria: https://www.medicalnewstoday.com/articles/322491.php
- the majority (as much as 95 percent) of the mood-influencing neurotransmitter serotonin is made and stored in the gut. Kevin Cann. “Low Serotonin and Gastrointestinal Disorders”. Robb Wolf Revolutionary Solutions to Modern Life. https://robbwolf.com/2013/01/10/serotonin-gastrointestinal-disorders/
- the enteric nervous system, whose main role is controlling digestion: “The Brain-Gut Connection”. Johns Hopkins Medicine.https://www.hopkinsmedicine.org/health/wellness-and-prevention/the-brain-gut-connection
- Constipation and depression in humans: “A Moody Gut Often Accompanies Depression:New Study Helps Explain Why”. Columbia University Irving Medical Center May 7, 2019. https://www.cuimc.columbia.edu/news/moody-gut-often-accompanies-depression-new-study-helps-explain-why
- the longest of the cranial nerves: Victoria Albina (2018). “Hack Your Vagus Nerve to Feel Better: 14 Easy Ways”. Victoria Albina July 5, 2018. https://victoriaalbina.com/vagusnerve/
- Escape through the intestinal wall and enter your bloodstream: Bruno Bonaz, Thomas Bazin, and Sonia Pellissier (2018). “The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis”. Frontiers in Neuroscience 2018; 12: 49. doi: 10.3389/fnins.2018.00049 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808284/
- Neurodegenerative disease in humans: Jiayi Zhao, Wei Bi, Shu Xiao, Xin Lan, Xiaofeng Cheng, Jiawei Zhang, Daxiang Lu, Wei Wei, Yanping Wang, Hongmei Li, Yongmei Fu & Lihong Zhu (2019). “Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice”. Scientific Reports April 8, 2019 doi: 10.1038/s41598-019-42286-8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453933/
- SIBO-induced brain fog: Dr. Michael Ruscio (2017). “How Your Gut Causes Brain Fog and How to Fix It”. Dr. Michael Ruscio, DNM, DC October 9 2017. https://drruscio.com/brain-fog/
- Chronic inflammation and histamine intolerance: Dr. Leonard Weinstock interview with the author.
- probiotics can help to boost your mood as well as your cognitive function while lowering levels of stress and anxiety: “Probiotics may help boost mood and cognitive function”. Harvard Health Publishing. https://www.health.harvard.edu/mind-and-mood/probiotics-may-help-boost-mood-and-cognitive-function
- linked not only brain fog but also extreme bloating to taking probiotics: Christopher Bergland. “In a Brain Fog? Probiotics Could Be the Culprit”. Psychology Today August 8, 2018. https://www.psychologytoday.com/us/blog/the-athletes-way/201808/in-brain-fog-probiotics-could-be-the-culprit
- The validity of that study has been rejected by the International Probiotics Association: Hank Schultz (2018). “IPA, other experts roundly reject conclusions of 'brain fog' paper”. Nutra Ingredients-USA.com August 13, 2018. https://www.nutraingredients-usa.com/Article/2018/08/13/Study-linking-probiotics-with-brain-fog-rejected-by-experts
- How probiotics can benefit SIBO patients: Dr. Jason Hawrelak interview with the author.
- Shown to be useful: Sabourin, Josh 2019). “Best Probiotics for SIBO”. https://sibosurvivor.com/best-probiotics-sibo/
- The most researched probiotic in the world: Alyssa M. Parian MD, ... Amy C. Brown PhD (2018). “Lactobacillus Rhamnosus”. Integrative Medicine (fourth edition) 2018.
- Outcomes and patients’ quality of life: Arko Banerjee, Sujit Sarkhel, Rajib Sarkar, and Gopal Krishna Dhali (2017). “Anxiety and Depression in Irritable Bowel Syndrome”. Indian Journal of Psychological Medicine 2017 Nov-Dec; 39(6): 741–745. doi: 10.4103/IJPSYM.IJPSYM_46_17
- then you can learn: Dr. Michael Ruscio, interview with the author
- Traumatizing to your brain: Summer Bock interview with the author
- A study done by the Mayo Clinic: https://www.mayoclinic.org/digestive-system/expert-answers/faq-20058340
- from the gastrointestinal tract: Mohammad H Farzaei, Roodabeh Bahramsoltani, Mohammad Abdollahi,* and Roja Rahimi (2016) “The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments”. Journal of Neurogastroenteroly and Motilty. 2016 Oct; 22(4): 558–574. doi: 10.5056/jnm16001 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056566/#__sec20title
- more intensely than other people : Dr. Megan Taylor interview with the author
- Dr. Crane Holmes: Interview with the author
- You’ll see what I mean: Dt. Jason Hawrelak interview with the author
- effectively but safely: Dr. Steven Sandberg-Lewis interview with the author
- Sits on top of the food you’ve eaten and prevents reflux: Dr. Michael Murray interview with the author
- Allows real healing to take place: Dr. Michael Murray interview with the author
- Decreasing leaky gut: Streit, Lizzie (2019). “What Is Colostrum? Nutrition, Benefits, and Downsides”. Healthline https://www.healthline.com/nutrition/bovine-colostrum
- muscles in the GI tract: Hui Li, Tian He, [...], and Cun-Zhi Liu (2015). “Acupuncture and regulation of gastrointestinal function”. World Journal of Gastroenterology 2015 Jul 21 21(27): 8304-8313.
- gastrointestinal motility in women after an abdominal hysterectomy gastrointestinal motility in women after trans-abdominal hysterectomy”. American Journal of Chinese Medicine 2003;31(5):781-90. DOI: 10.1142/S0192415X03001466 https://www.ncbi.nlm.nih.gov/pubmed/14696681
- To treat both constipation and diarrhea in people with irritable bowel syndrome: https://www.the-elbowroom.com/useful-information/conditions-reflexology-helps/
- Feel better in the here-and-now: “Hypnosis for IBS”. International Foundation for Gastrointestinal Disorders 28 August 2018. https://www.aboutibs.org/complimentary-or-alternative-treatments/hypnosis-for-ibs.html
- Sleep.org also suggests: https://www.sleep.org/articles/temperature-for-sleep/
- melatonin supplements: Kewin Tien Ho Siah, Reuben Kong Min Wong, and Khek Yu Ho (2014). “Melatonin for the treatment of irritable bowel syndrome”. World Journal of Gastroenterology 2014 Mar 14; 20(10): 2492–2498. doi: 10.3748/wjg.v20.i10.2492
- created at Monash University in Melbourne, Australia: The Low FODMAP Diet. https://www.monashfodmap.com/
- The ratio of fructose to glucose in these forms of honey: Dr. Allison Siebecker interview with the author
- Bloating, flatulence, and loose stools: Stephanie Ferguson. “Facts About Fructose Absorption and Tolerance”, International Food Information Council Foundation January 11, 2012 https://foodinsight.org/facts-about-fructose-absorption-and-tolerance/
- All that eating the wrong foods can do: Dr. Allison Siebecker interview with the author
- there is a clear relationship between alcoholism and clinical depression: https://www.webmd.com/depression/guide/alcohol-and-depresssion#1
- Foods such as avocado and onion: Dr. Allison Siebecker interview with author
- The more foods you can eat without being sick: Dr. Allison Siebecker interview with the author
- I just can’t tolerate pumpkin: Rebecca Coomes interview with the author
- either neomycin or metronidazole: Low K, Hwang L, Hua J, Zhu A, Morales W, Pimentel M. (2010). “A combination of rifaximin and neomycin is most effective in treating irritable bowel syndrome patients with methane on lactulose breath test”. Journal of Clinical Gastroenterology 2010 Sep;44(8):547-50. doi: 10.1097/MCG.0b013e3181c64c90. https://www.ncbi.nlm.nih.gov/pubmed/19996983
- help with the constipation type of SIBO: Dr. Mark Pimentel interview with the author
- and Dr. Siebecker explained to me: Dr. Allison Siebecker interview with author
- An eradication rate of 87 percent: M. Furnari, A. Parodi, L. Gemignani, E. G. Giannini, S. Marenco, E. Savarino, L. Assandri, V. Fazio, D. Bonfanti, S. Inferrera, V. Savarino (2010). “Clinical trial: the combination of rifaximin with partially hydrolysed guar gum is more effective than rifaximin alone in eradicating small intestinal bacterial overgrowth”, Alimentary Pharmacology and Therapeutics. First published:18 August 2010 https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2036.2010.04436.x
- Most do not develop resistance to it: Farrell DJ (2013). “Rifaximin in the treatment of irritable bowel syndrome: is there a high risk for development of antimicrobial resistance?”, Journal of Clinical Gastroenterology. 2013 Mar;47(3):205-11. doi: 10.1097/MCG.0b013e31827559a3. https://www.ncbi.nlm.nih.gov/pubmed/23340064
- irreversible hearing loss: https://www.uofmhealth.org/health-library/d00312a1
- Effective than pharmaceuticals: Chedid V, Dhalla S, Clarke JO, Roland BC, Dunbar KB, Koh J, Justino E, Tomakin E, Mullin GE (2014). “Herbal therapy is equivalent to rifaximin for the treatment of small intestinal bacterial overgrowth”, Global Advances in Health and Medicine. 2014 May;3(3):16-24. doi: 10.7453/gahmj.2014.019 https://www.ncbi.nlm.nih.gov/pubmed/24891990
- Victor Chedid, MD, Sameer Dhalla, MD, John O. Clarke, MD, Bani Chander Roland, MD, Kerry B. Dunbar, MD, Joyce Koh, MD, Edmundo Justino, MD, Eric Tomakin, RN, and Gerard E. Mullin, MD (2014). “Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth”. Global Advances in Health Medicine 2014 May; 3(3): 16–24. doi: 10.7453/gahmj.2014.019. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030608/
- Keep taking them permanently: Dr. Allison Siebecker with the author
- Infections are associated with biofilms: Römling U, Balsalobre C. (2012). “Biofilm infections, their resilience to therapy and innovative treatment strategies”. Journal of Internal Medicine 2012 Dec;272(6):541-61. doi: 10.1111/joim.12004. https://www.ncbi.nlm.nih.gov/pubmed/23025745
- more powerful treatments: Dt. Michael Ruscio (2018). “Biofilms Can Cause Infections That Won’t Clear – What to Do About It with Dr. Paul Anderson”. Dr. Ruscio Blog February 14, 2018. https://drruscio.com/biofilms-can-cause-infections-with-dr-paul-anderson/
- Positive for SIBO: Rezaie A, Buresi M, Lembo A, Lin H, McCallum R, Rao S, Schmulson M, Valdovinos M, Zakko S, Pimentel M (2017). “Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus”. American Journal of Gastroenterology. 2017 May;112(5):775-784. doi: 10.1038/ajg.2017.46. https://www.ncbi.nlm.nih.gov/pubmed/28323273
- Start thinking about things that are causing the SIBO: Dr. Mark Pimentel interview with the author
- Prevention and treatment of autoimmunity: Aglaée Jacob, MS, RD (2013). “Gut Health and Autoimmune Disease — Research Suggests Digestive Abnormalities May Be the Underlying Cause”. Today’s Dietician. February 2013. https://www.todaysdietitian.com/newarchives/021313p38.shtml
- that you have the condition: Dr. Leonard Weinstock interview with the author
- Get tested for Lyme disease: Dr. Tom Messinger interview with the author
- SIBO Specific Food Guide: Compiled by Dr. Allison Siebecker (www.siboinfo.com)
Praise for Healing SIBO
“By combining cutting-edge technical and medical information from health experts with her own expert advice and insights as a patient who has been there herself, Shivan has created an invaluable resource for the millions of people struggling with SIBO. I highly recommend Healing SIBO.” ~ Dr. Allison Siebecker
“Shivan has done more to help SIBO patients understand and heal their condition than anyone. Her mission is to educate the public on the most cutting edge information about SIBO treatments and this book is no exception. This is your one-stop guide to everything you need to know about living with and treating SIBO.” ~ Dr. Ilana Gurevich
“Healing SIBO is just like Shivan – very organized, full of insight, painstakingly researched, highly practical and imbued with warm-hearted fun.” ~ Dr. Steven Sandberg-Lewis
“Healing SIBO is an amazing contribution to those diagnosed with SIBO as well as those who are just beginning to address their gastrointestinal issues. Shivan Sarna has worked with the best doctors, nutritionists and other healthcare practitioners in the SIBO community for years and it shows in the wealth of information that she presents in this book. She offers practical advice and breaks down the intricacies of healing from SIBO to make it accessible to everyone.” ~ Kristy Regan, MScN
“Ms. Sarna has written an absolute gem of a book. As a sufferer of SIBO herself she includes tips and tricks for understanding SIBO and IBS from the inside out. She takes an incredible amount of information that can be overwhelming and turns it into an easily digestible and incredibly rich resource for not only the SIBO patient but also for physicians who need to understand what options their patients have for diagnostic testing and treatment of this disorder. Ms. Sarna has taken her access to interviewing all of the top clinicians and researchers in the SIBO landscape and has synthesized that information in a way that the reader can access all of the most comprehensive and uptodate ideas around testing, treatment and understanding of their health picture. This is a must-read.” ~ Dr. Anne Hill
“Shivan Sarna’s new book, Healing SIBO: Fix the Real Cause of IBS, Bloating, and Weight Issues in 21 Days, has a powerful dedication at it’s very beginning: “To anyone who has ever had a medical mystery.” Having spent over a decade as a Naturopathic Doctor treating medical mysteries, I say this book – a guidebook to overcoming SIBO – is long overdue. SIBO has been a medical mystery disrupting millions of lives around the world. In addition to a plan to eradicate SIBO, this book powerfully outlines the hurdles. Like so many chronic illnesses, one of the main obstacles is that it mirrors the symptoms of many other disorders, leaving it underdiagnosed and untreated. Make no mistake, the domino effect of SIBO is not just a digestive inconvenience or bloating, it is also often responsible for food allergies, as well as simultaneously causing weight gain AND malnutrition. In a world where Google floods us with more information than we could absorb in a lifetime (never mind discerning what is accurate and relevant to your own health journey), Shivan Sarna has broken down the causes, the condition, and most importantly, provided a step-by-step simple pathway back to health. Healing SIBO is a must-read for anyone navigating SIBO, digestive issues, or unexplained symptoms.” ~ Dr. Christine Schaffner
“Healing SIBO contains the practical steps a patient needs to take to get well. Shivan has interviewed and distilled the best practitioners in SIBO world to create a book that any IBS person should own. After reading this you’ll end up knowing more about SIBO than 99% of doctors. Which is very important because healing from chronic conditions takes a multifactorial approach that Shivan lays out. If you think getting rid of SIBO is just about the right tests and killing protocols you’re missing 50% of the getting well map.” ~ Steven Wright (HealthyGut.com)
About The Author
Shivan Sarna
I’m Shivan Sarna and over the past 20 years you may have seen me as a TV Host (especially if you like shopping). So how did I end up at SIBO SOS?
After a lifetime of digestive problems, I was diagnosed with Small Intestine Bacterial Overgrowth in 2015. I was so excited to finally have a name for the symptoms that made me miserable – but I was quickly very frustrated by how hard it was to get access to reliable SIBO information, or even an appointment with a doctor who had experience treating SIBO. I set out to get answers about SIBO for myself – but along the way, I met hundreds (and then thousands) of other people like you who had the same problems: How do we find experts who really understand SIBO? What do we do if we can’t travel to see one these experts? Will we have to suffer forever?
I went back to my roots as an advocate and educator focusing on bringing the experts together in one place to teach all of us: that’s how SIBO SOS® was born.
After finding the answers for myself, I created SIBO SOS®, four summits, and a documentary all about how to heal from SIBO and gut issues. Then I wrote my book, “Healing SIBO” to get the answers to YOU. In your journey to understand, treat, and manage IBS, SIBO, and other digestive issues, I’m your guide, advocate, support, and shoulder to cry on – I’ll give you a nudge, introduce you to the people with the answers, and always be here to encourage you.
I want to save you time, energy and money by giving you the expert answers in a concise way.
Get the answers you need so you can start healing and get back to life!
